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Article

Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.

Genes & development - 1 Jan 1999

Ranish J A, Yudkovsky N, Hahn S

Abstract excerpt

Assembly and activity of yeast RNA polymerase II (Pol II) preinitiation complexes (PIC) was investigated with an immobilized promoter assay and extracts made from wild-type cells and from cells containing conditional mutations in components of the Pol II machinery. We describe the following findi...

Topics

Fungal Proteins
Mutation
Promoter Regions, Genetic
Protein Binding
RNA Polymerase II
TATA Box
Trans-Activators
Transcription Factor TFIIA
Transcription Factor TFIIB
Transcription Factor TFIID
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors, TFII

Transcription, Genetic

Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 9887099
DOI: 10.1101/gad.13.1.49
PMCID: PMC316368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9887099-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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