Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain.

doi:10.1038/374820a0

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Article

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain.

Nature - 27 Apr 1995

Chatterjee S, Struhl K

Abstract excerpt

Biochemical analyses have suggested potential targets for transcriptional activation domains, which include several components of the RNA polymerase II machinery, as well as the chromatin template. Here we examine the mechanism of transcriptional activation in yeast cells by connecting a heterolo...

Topics

Bacterial Proteins
DNA-Binding Proteins
Mutation
Promoter Regions, Genetic
Protein Binding
Saccharomyces cerevisiae
Serine Endopeptidases
TATA Box
TATA-Box Binding Protein
Transcription Factors
Transcriptional Activation

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