Article
TBP-associated factors are not generally required for transcriptional activation in yeast.
Nature - 12 Sept 1996
Moqtaderi Z, Bai Y, Poon D, Weil P A, Struhl K
Abstract excerpt
The transcription factor TFIID, a central component of the eukaryotic RNA polymerase II (Pol II) transcription apparatus, comprises the TATA-binding protein (TBP) and approximately ten TBP-associated factors (TAFs). Although the essential role of TBP in all eukaryotic transcription has been extensively analysed in vivo and in vitro, the function of the TAFs is less clear. In vitro, TAFs are dispensable for basal...
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