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Article

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes.

Growth factors (Chur, Switzerland) - 1 Jan 1999

Rosenkranz S, Kazlauskas A

Abstract excerpt

Platelet-derived growth factor (PDGF) acts as a potent mitogen, chemoattractant and survival factor for mesenchymal cells. In addition to its importance in mammalian development, PDGF plays a critical role in physiological repair mechanisms and in the pathogenesis of various proliferative diseases. The biological effects of PDGF are initiated via two related receptor tyrosine kinases, termed alpha and betaPDGF...

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Identifiers

PMID: 10372961
DOI: 10.3109/08977199909002130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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