Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PDGF-C and PDGF-D signaling in vascular diseases and animal models.

Molecular aspects of medicine - 1 Aug 2018

Folestad Erika, Kunath Anne, Wågsäter Dick

Abstract excerpt

Members of the platelet-derived growth factor (PDGF) family are well known to be involved in different pathological conditions. The cellular and molecular mechanisms induced by the PDGF signaling have been well studied. Nevertheless, there is much more to discover about their functions and some important questions to be answered. This review summarizes the known roles of two of the PDGFs, PDGF-C and PDGF-D, in...

Topics

Animals
Cardiovascular System
Disease Models, Animal
Gene Expression Regulation
Humans
Lymphokines
Neovascularization, Physiologic
Platelet-Derived Growth Factor
Polymorphism, Single Nucleotide
Receptor, Platelet-Derived Growth Factor alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, Platelet-Derived Growth Factor beta

Signal Transduction

Vascular Diseases

Source

Identifiers

PMID: 29410092
DOI: 10.1016/j.mam.2018.01.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PDGF-C and PDGF-D signaling in vascular diseases and animal models.PMID 29410092Read ↗

Roles of PDGF/PDGFR signaling in various organsSemantic proximity Read ↗

Role of platelet-derived growth factors in physiology and medicine.Semantic proximity Read ↗

Platelet-derived Growth Factor Signaling and Human CancerSemantic proximity Read ↗

Structural and functional specificities of PDGF‐C and PDGF‐D, the novel members of the platelet‐derived growth factors familySemantic proximity Read ↗

PDGF receptor signaling networks in normal and cancer cellsSemantic proximity Read ↗

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes.Semantic proximity Read ↗

Pathogenetic significance and possibility as a therapeutic target of platelet derived growth factorSemantic proximity Read ↗

Signaling Role of Pericytes in Vascular Health and Tissue HomeostasisSemantic proximity Read ↗

New insights about the PDGF/PDGFR signaling pathway as a promising target to develop cancer therapeutic strategiesSemantic proximity Read ↗

Insight into the physiological functions of PDGF through genetic studies in mice.Semantic proximity Read ↗

PDGF and cardiovascular diseaseSemantic proximity Read ↗

Autocrine PDGF stimulation in malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.