Article
Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms.
Matrix biology : journal of the International Society for Matrix Biology - 1 Apr 1999
Wang X, Tromp G, Cole C W, Verloes A, Sakalihasan N, Yoon S, Kuivaniemi H
Abstract excerpt
Aneurysms are characterized by dilation, i.e. expansion and thinning of all the arterial wall layers, which is accompanied by remodeling of the connective tissue. Genes involved in the regulation of tissue remodeling are therefore candidate genes. We analyzed TIMP1 and TIMP2 coding sequences in 12 individuals with abdominal aortic aneurysms (AAA), one individual with AAA and intracranial aneurysms (IA), four...
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