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Article

Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm.

Journal of vascular surgery - 1 Jan 2012

Saracini Claudia, Bolli Paola, Sticchi Elena, Pratesi Giovanni, Pulli Raffaele, Sofi Francesco, Pratesi Carlo, Gensini Gian Franco, Abbate Rosanna, Giusti Betti

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysm (AAA) has a multifactorial etiology and the relevance of genetic factors is getting increasing interest, in particular those related to the destructive remodeling of extracellular matrix. METHODS: We performed a candidate gene association study of polymorphisms in genes coding matrix metalloproteinases (MMPs), tissue inhibitors of MMPs (TIMPs), and elastin (ELN) in AAA. DNA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22094117
DOI: 10.1016/j.jvs.2011.07.051

Genes

ELN
MMP2
MMP3
TIMP1
MMP1
MMP10
MMP9
TIMP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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