Article

Genome-Wide Association Study of the Relationship Between Matrix Metalloproteinases and Intracranial Aneurysms

2022-01-01

Abstract excerpt

Matrix metalloproteinases (MMPs) are expected to play an important role in extracellular matrix (ECM) remodeling in response to hemodynamic stress. We investigated the association between MMPs and intracranial aneurysms (IAs) via a genome-wide association study (GWAS) of IAs.A GWAS data set of 250 IAs and 294 controls was used to analyze the genetic link between MMPs and IAs via single-nucleotide polymorphisms (SN...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 95e40c2a-7458-5a37-9cb9-3da322dc4134
DOI: 10.3988/jcn.2022.18.2.163

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association Study of the Relationship Between Matrix Metalloproteinases and Intracranial AneurysmsDOI 10.3988/jcn.2022.18.2.163Read

Association of functional MMP-2 gene variant with intracranial aneurysms: case-control genetic association study and meta-analysis.Semantic proximity Read

The association between collagen gene polymorphisms and intracranial aneurysms: a meta-analysis.Semantic proximity Read

Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.Semantic proximity Read

Genetic study of intracranial aneurysms.Semantic proximity Read

Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular diseaseSemantic proximity Read

Intracranial Aneurysm Biomarkers: A Convergence of Genetics, Inflammation, Oxidative Stress, and the Extracellular MatrixSemantic proximity Read

Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.Semantic proximity Read

Intracranial Aneurysms and Genetics: An Extensive Overview of Genomic Variations, Underlying Molecular Dynamics, Inflammatory Indicators, and Forward-Looking InsightsSemantic proximity Read

The rs1333040 and rs10757278 9p21 locus polymorphisms in patients with intracranial aneurysm: a meta-analysis.Semantic proximity Read

Molecular genetics of human intracranial aneurysms.Semantic proximity Read

Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization ResearchSemantic proximity Read

Genetic factors involves in intracranial aneurysms--actualities.Semantic proximity Read