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Article

Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms.

Journal of vascular surgery - 1 Jun 2005

Ogata Toru, Shibamura Hidenori, Tromp Gerard, Sinha Moumita, Goddard Katrina A B, Sakalihasan Natzi, Limet Raymond, MacKean Gerald L, Arthur Claudette, Sueda Taijiro, Land Susan, Kuivaniemi Helena

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysms (AAAs) are characterized by histologic signs of chronic inflammation, destructive remodeling of extracellular matrix, and depletion of vascular smooth muscle cells. We investigated the process of extracellular matrix remodeling by performing a genetic association study with polymorphisms in the genes for matrix metalloproteinases (MMPs), tissue inhibitors of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15944607
DOI: 10.1016/j.jvs.2005.02.020
PMCID: PMC1249499

Genes

TIMP1
ELN
MMP10
TIMP3
MMP9
MMP1
MMP12
MMP13
MMP2
MMP3
TGFB1
TIMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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