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Article

Tissue inhibitor of metalloproteinases-1, -2, and -3 polymorphisms in a white population with intracranial aneurysms.

Stroke - 1 Dec 2003

Krex Dietmar, Röhl Henning, König Inke R, Ziegler Andreas, Schackert Hans K, Schackert Gabriele

Abstract excerpt

BACKGROUND AND PURPOSE: Remodeling of the extracellular matrix seems to be a crucial event in the pathogenesis of cerebral aneurysms. Matrix metalloproteinases are the most important degrading enzymes in the extracellular matrix. Their activity is controlled predominantly by tissue inhibitors of metalloproteinases (TIMPs). To investigate the possible impact of genetic variants within the genes encoding TIMP-1,...

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Identifiers

PMID: 14605322
DOI: 10.1161/01.STR.0000099966.51485.5F

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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