Article
[Analysis of tissue inhibitor of metalloproteinase-2 gene polymorphisms in a caucasian population with abdominal aortic aneurysms].
Zentralblatt fur Chirurgie - 1 Aug 2008
Hinterseher I, Krex D, Kuhlisch E, Pilarsky C, Schneiders W, Saeger H D, Bergert H
Abstract excerpt
BACKGROUND: The formation of sporadic abdominal aortic aneurysm (AAA) is explained by a remodelling of the extracellular matrix (ECM) and breakdown of structural components of the vascular wall. Matrix metalloproteinases are the principle matrix-degrading proteases and are known to play a major r...
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