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Article

Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stability.

The EMBO journal - 1 Jun 1999

Vilela C, Ramirez C V, Linz B, Rodrigues-Pousada C, McCarthy J E

Abstract excerpt

A novel form of post-transcriptional control is described. The 5' untranslated region (5'UTR) of the Saccharomyces cerevisiae gene encoding the AP1-like transcription factor Yap2 contains two upstream open reading frames (uORF1 and uORF2). The YAP2-type of uORF functions as a cis-acting element that attenuates gene expression at the level of mRNA turnover via termination-dependent decay. Release of...

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Source

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Identifiers

PMID: 10357825
DOI: 10.1093/emboj/18.11.3139
PMCID: PMC1171395

Genes

UPF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Post-termination ribosome interactions with the 5'UTR modulate yeast mRNA stability.PMID 10357825Read ↗

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