Article
Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 1999
Leitinger N, Watson A D, Hama S Y, Ivandic B, Qiao J H, Huber J, Faull K F, Grass D S, Navab M, Fogelman A M, de Beer F C, Lusis A J, Berliner J A
Abstract excerpt
Secretory nonpancreatic phospholipase A2 (group II sPLA2) is induced in inflammation and present in atherosclerotic lesions. In an accompanying publication we demonstrate that transgenic mice expressing group II sPLA2 developed severe atherosclerosis. The current study was undertaken to determine whether 1 mechanism by which group II sPLA2 might contribute to the progression of inflammation and atherosclerosis is...
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