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Article

Spontaneous mutation at position 114 in H-2Kd affects cytotoxic T cell responses to influenza virus infection.

European journal of immunology - 1 Apr 1999

Müllbacher A, Lobigs M, Yewdell J W, Bennink J R, Tha Hla R, Blanden R V

Abstract excerpt

Vaccinia virus (VV)-encoded MHC class I Kd molecules which differ by a single amino acid change from glutamine (Kdw, wild type) to histidine (Kdm, mutant) at position 114 located in the floor of the peptide binding groove were compared in terms of peptide binding and cytotoxic T (Tc) cell recognition. Most anti-viral Tc cells were not affected or only marginally affected. However, the Kdm molecule did not...

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Source

Identifiers

PMID: 10229090
DOI: 10.1002/(SICI)1521-4141(199904)29:04<1228::AID-IMMU1228>3.0.CO;2-L

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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