Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a new element for RNA replication within the internal ribosome entry site of poliovirus RNA.

The Journal of general virology - 1 Apr 1999

Ishii T, Shiroki K, Iwai A, Nomoto A

Abstract excerpt

Several mutants of the Mahoney strain of poliovirus type 1 have been generated by introducing mutations into the stem-loop II (SLII) structure within the internal ribosomal entry site (IRES). Four of these mutants (SLII-1, -4, -5 and -6 mutants) have been characterized previously and are host-range mutants that replicate well in human HeLa cells but not in mouse cells. Two deletion mutants, SLII-2 and SLII-3,...

Topics

HeLa Cells
Humans
Molecular Weight
Mutation
Poliovirus
RNA, Viral
Ribosomes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10211960
DOI: 10.1099/0022-1317-80-4-917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a new element for RNA replication within the internal ribosome entry site of poliovirus RNA.PMID 10211960Read ↗

A new internal ribosomal entry site 5' boundary is required for poliovirus translation initiation in a mouse system.Semantic proximity Read ↗

Minimum internal ribosome entry site required for poliovirus infectivity.Semantic proximity Read ↗

Host range phenotype induced by mutations in the internal ribosomal entry site of poliovirus RNA.Semantic proximity Read ↗

Functional Insights into the Adjacent Stem-Loop in Honey Bee Dicistroviruses That Promotes Internal Ribosome Entry Site-Mediated Translation and Viral InfectionSemantic proximity Read ↗

An RNA hairpin at the extreme 5' end of the poliovirus RNA genome modulates viral translation in human cells.Semantic proximity Read ↗

Poliovirus internal ribosome entry segment structure alterations that specifically affect function in neuronal cells: molecular genetic analysis.Semantic proximity Read ↗

A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA.Semantic proximity Read ↗

An Internal Ribosome Entry Segment Promotes Translation of the Simian Immunodeficiency Virus Genomic RNASemantic proximity Read ↗

Glycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiation.Semantic proximity Read ↗

Structure and function analysis of the poliovirus <i>cis</i>-acting replication element (CRE)Semantic proximity Read ↗

Identification of a novel internal ribosome entry site in giardiavirus that extends to both sides of the initiation codon.Semantic proximity Read ↗

Structural elements in the internal ribosome entry site of Plautia stali intestine virus responsible for binding with ribosomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.