A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA.

doi:10.1128/JVI.69.11.6825-6832.1995

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA.

Journal of virology - 1 Nov 1995

Shiroki K, Ishii T, Aoki T, Kobashi M, Ohka S, Nomoto A

Abstract excerpt

Mouse cells expressing the human poliovirus receptor (PVR-mouse cells) as well as human HeLa cells are susceptible to poliovirus type 1 Mahoney strains and produce a large amount of progeny virus at 37 degrees C. However, the virus yield is markedly reduced at 40 degrees C in PVR-mouse cells but not in HeLa cells. The reduction in virus yield at 40 degrees C appears to be due to a defective initiation process in...

Topics

Animals
Base Sequence
Cell Line
Cloning, Molecular
DNA Primers
HeLa Cells
Humans
Kinetics
L Cells
Mice
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Conformation

Poliovirus

Polymerase Chain Reaction

RNA, Viral

Time Factors

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 7474095
DOI: 10.1128/JVI.69.11.6825-6832.1995
PMCID: PMC189595

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7474095-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new cis-acting element for RNA replication within the 5' noncoding region of poliovirus type 1 RNA.PMID 7474095Read ↗

A new internal ribosomal entry site 5' boundary is required for poliovirus translation initiation in a mouse system.Semantic proximity Read ↗

Host range phenotype induced by mutations in the internal ribosomal entry site of poliovirus RNA.Semantic proximity Read ↗

Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence.Semantic proximity Read ↗

Identification of a new element for RNA replication within the internal ribosome entry site of poliovirus RNA.Semantic proximity Read ↗

The 3′ <i>cis</i> -Acting Genomic Replication Element of the Severe Acute Respiratory Syndrome Coronavirus Can Function in the Murine Coronavirus GenomeSemantic proximity Read ↗

Functional dissection of a poliovirus cis-acting replication element [PV-cre(2C)]: analysis of single- and dual-cre viral genomes and proteins that bind specifically to PV-cre RNA.Semantic proximity Read ↗

Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylation.Semantic proximity Read ↗

trans rescue of a mutant poliovirus RNA polymerase functionSemantic proximity Read ↗

Preliminary characterization of cis interactions between mutations of poliovirus genome.Semantic proximity Read ↗

Mouse adaptation determinants of poliovirus type 1 enhance viral uncoating.Semantic proximity Read ↗

Mutational Analysis of the Uukuniemi Virus ( Bunyaviridae Family) Promoter Reveals Two Elements of Functional ImportanceSemantic proximity Read ↗

A cis-acting element within the hepatitis A virus 5'-non-coding region required for in vitro translation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.