Article
Minimum internal ribosome entry site required for poliovirus infectivity.
Journal of virology - 1 Dec 1993
Haller A A, Nguyen J H, Semler B L
Abstract excerpt
Translation initiation by internal ribosome binding is a recently discovered mechanism of eukaryotic viral and cellular protein synthesis in which ribosome subunits interact with the mRNAs at internal sites in the 5' untranslated RNA sequences and not with the 5' methylguanosine cap structure pre...
Topics
- Cross-Linking Reagents
- Genetic Engineering
- HeLa Cells
- Humans
- Mutation
- Nucleic Acid Conformation
- Peptide Chain Initiation, Translational
- Poliovirus
- RNA, Messenger
- RNA, Viral
- Regulatory Sequences, Nucleic Acid
- Ribosomes
- Sequence Analysis, RNA
- Transfection
- Ultraviolet Rays
- Viral Plaque Assay
- Viral Proteins
- Virulence