Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of a novel internal ribosome entry site in giardiavirus that extends to both sides of the initiation codon.

The Journal of biological chemistry - 30 Jan 2004

Garlapati Srinivas, Wang Ching C

Abstract excerpt

In Giardia lamblia, enhanced translation of luciferase mRNA, flanked between the 5'-untranslated region (UTR) and 3 '-end of giardiavirus transcript, requires the presence of the initial 264-nucleotide (nt) viral capsid-coding region. By introducing the transcripts of dicistronic viral constructs into Giardia, we demonstrated that the 264-nt downstream region alone is insufficient to function as an internal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Blotting, Northern
Share to Codon, Initiator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Luciferases

Share to Nucleic Acid Conformation

Share to Protein Biosynthesis

Share to Ribosomes

Source

Identifiers

PMID: 14615487
DOI: 10.1074/jbc.M307565200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a novel internal ribosome entry site in giardiavirus that extends to both sides of the initiation codon.PMID 14615487Read ↗

The sequence context of the initiation codon in the encephalomyocarditis virus leader modulates efficiency of internal translation initiationSemantic proximity Read ↗

Functional Characterization of the Internal Ribosome Entry Site of eIF4G mRNASemantic proximity Read ↗

A Distinct Class of Internal Ribosomal Entry Site in Members of the Kobuvirus and Proposed Salivirus and Paraturdivirus Genera of the PicornaviridaeSemantic proximity Read ↗

In Vivo and In Vitro Identification of Structural and Sequence Elements of the Human Parechovirus 5′ Untranslated Region Required for Internal InitiationSemantic proximity Read ↗

Involvement of the 5' proximal coding sequences of hepatitis C virus with internal initiation of viral translation.Semantic proximity Read ↗

Dissemination of Internal Ribosomal Entry Sites (IRES) Between Viruses by Horizontal Gene TransferSemantic proximity Read ↗

Specific secondary structures in the capsid-coding region of giardiavirus transcript are required for its translation in Giardia lamblia.Semantic proximity Read ↗

Initiation of translation on nedicistrovirus and related intergenic region IRESs by their factor-independent binding to the P site of 80S ribosomesSemantic proximity Read ↗

Functional Insights into the Adjacent Stem-Loop in Honey Bee Dicistroviruses That Promotes Internal Ribosome Entry Site-Mediated Translation and Viral InfectionSemantic proximity Read ↗

Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation on hepatitis C virus RNA.Semantic proximity Read ↗

Exploring Internal Ribosome Entry Sites as Therapeutic TargetsSemantic proximity Read ↗

RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA TranslationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.