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Article

Gli genes and limb development.

Cell and tissue research - 1 Apr 1999

Theil T, Kaesler S, Grotewold L, Böse J, Rüther U

Abstract excerpt

During development of the limb Shh plays a key role as a mediator of zone of polarizing activity (ZPA). However, the molecular mechanisms by which Shh directs anterior/posterior patterning in the limb remain unknown. Members of the Gli gene family encode zinc-finger transcription factors and represent likely candidates for being regulators of Shh target genes. In this review we would like to summarize the current...

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Identifiers

PMID: 10199967
DOI: 10.1007/s004410051268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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