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The Hedgehog Signal Transduction Network

16 Oct 2012

Abstract excerpt

Hedgehog (Hh) proteins regulate the development of a wide range of metazoan embryonic and adult structures, and disruption of Hh signaling pathways results in various human diseases. Here, we provide a comprehensive review of the signaling pathways regulated by Hh, consolidating data from a diverse array of organisms in a variety of scientific disciplines. Similar to the elucidation of many other signaling...

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PMID: 23074268
DOI: 10.1126/scisignal.2002906

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