Article
The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers.
RNA (New York, N.Y.) - 1 Mar 1999
Cavaloc Y, Bourgeois C F, Kister L, Stévenin J
Abstract excerpt
The activity of the SR protein family of splicing factors in constitutive or alternative splicing requires direct interactions with the pre-mRNA substrate. Thus it is important to define the high affinity targets of the various SR species and to evaluate their ability to discriminate between defined RNA targets. We have analyzed the binding specificity of the 30-kDa SR protein 9G8, which contains a zinc knuckle...
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