Article
Pre-mRNA splicing in the absence of an SR protein RS domain.
Genes & development - 15 Dec 2000
Zhu J, Krainer A R
Abstract excerpt
SR proteins are essential pre-mRNA splicing factors that act at the earliest stages of splice-site recognition and spliceosome assembly, as well as later in the splicing pathway. SR proteins consist of one or two RNA-recognition motifs and a characteristic arginine/serine-rich C-terminal RS domain. The RS domain, which is extensively phosphorylated, mediates the subcellular localization of individual SR proteins...
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