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Article

Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity.

The Journal of cell biology - 28 Jul 1997

Cáceres J F, Misteli T, Screaton G R, Spector D L, Krainer A R

Abstract excerpt

SR proteins are required for constitutive pre-mRNA splicing and also regulate alternative splice site selection in a concentration-dependent manner. They have a modular structure that consists of one or two RNA-recognition motifs (RRMs) and a COOH-terminal arginine/serine-rich domain (RS domain). We have analyzed the role of the individual domains of these closely related proteins in cellular distribution,...

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Identifiers

PMID: 9230067
DOI: 10.1083/jcb.138.2.225
PMCID: PMC2138183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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