Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation.

doi:10.1074/jbc.M413793200

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Article

Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation.

The Journal of biological chemistry - 13 May 2005

Zhang Shu Xing, Garcia-Gras Eduardo, Wycuff Diane R, Marriot Suzanne J, Kadeer Nijiati, Yu Wei, Olson Eric N, Garry Daniel J, Parmacek Michael S, Schwartz Robert J

Abstract excerpt

Serum-response factor (SRF) is an obligatory transcription factor, required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Protein A-TEV-tagged chromatin immunoprecipitation technology was used to collect direct SRF-bound gene targets from pluripotent P19 cells, induced by Me2SO treatment into an enriched cardiac cell population. From 242 sequenced DNA fragments, we...

Topics

Amino Acid Motifs
Animals
Binding Sites
Blotting, Western
Cell Differentiation
Cell Line
Chromatin
Chromatin Immunoprecipitation
Cloning, Molecular
DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Databases as Topic

Dimethyl Sulfoxide

Down-Regulation

Electrophoresis, Polyacrylamide Gel

Gene Expression Regulation

Genes, Reporter

Genetic Vectors

Genome

Source

Open in PubMed

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PMID: 15699019
DOI: 10.1074/jbc.M413793200

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