Article
Interactions of SR45, an SR-like protein, with spliceosomal proteins and an intronic sequence: insights into regulated splicing.
The Plant journal : for cell and molecular biology - 1 Sept 2012
Day Irene S, Golovkin Maxim, Palusa Saiprasad G, Link Alicia, Ali Gul S, Thomas Julie, Richardson Dale N, Reddy Anireddy S N
Abstract excerpt
SR45 is a serine/arginine-rich (SR)-like protein with two arginine/serine-rich (RS) domains. We have previously shown that SR45 regulates alternative splicing (AS) by differential selection of 5' and 3' splice sites. However, it is unknown how SR45 regulates AS. To gain mechanistic insights into the roles of SR45 in splicing, we screened a yeast two-hybrid library with SR45. This screening resulted in the...
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