Article
Allowing for missing parents in genetic studies of case-parent triads.
American journal of human genetics - 1 Apr 1999
Weinberg C R
Abstract excerpt
In earlier work, my colleagues and I described a log-linear model for genetic data from triads composed of affected probands and their parents. This model allows detection of and discrimination between effects of an inherited haplotype versus effects of the maternal haplotype, which presumably would be mediated by prenatal factors. Like the transmission disequilibrium test (TDT), the likelihood-ratio test (LRT)...
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