Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Testing informative missingness in genetic studies using case-parent triads.

European journal of human genetics : EJHG - 1 Aug 2008

Guo Chao-Yu, Cupples Laura Adrienne, Yang Qiong

Abstract excerpt

In genetic studies, the transmission/disequilibrium test (TDT) using case-parent triads has gained popularity attributable to its robustness to population admixture. Several extensions have been proposed to accommodate incomplete triads. Some strategies assume that parental genotypes are missing completely at random (MCAR) to insure an unbiased conclusion and some methods allow parental genotypes to be missing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Computer Simulation
Share to Genetic Diseases, Inborn

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Linkage Disequilibrium

Share to Models, Statistical

Share to Parents

Share to Probability

Source

Identifiers

PMID: 18337731
DOI: 10.1038/ejhg.2008.38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Testing informative missingness in genetic studies using case-parent triads.PMID 18337731Read ↗

A novel test of informative missingness using inconsistent linkage disequilibrium signals between case-parent triads and incomplete data.Semantic proximity Read ↗

Allowing for missing parents in genetic studies of case-parent triads.Semantic proximity Read ↗

New approach to association testing in case-parent designs under informative parental missingness.Semantic proximity Read ↗

Informative missingness in genetic association studies: case-parent designs.Semantic proximity Read ↗

Rare variant association analysis in case-parents studies by allowing for missing parental genotypes.Semantic proximity Read ↗

A robust TDT-type association test under informative parental missingness.Semantic proximity Read ↗

Impact of non-ignorable missingness on genetic tests of linkage and/or association using case-parent trios.Semantic proximity Read ↗

Haplotype analysis in the presence of informatively missing genotype data.Semantic proximity Read ↗

Expectation maximization algorithm based haplotype relative risk (EM-HRR): test of linkage disequilibrium using incomplete case-parents trios.Semantic proximity Read ↗

Method for using complete and incomplete trios to identify genes related to a quantitative trait.Semantic proximity Read ↗

Disentangling pooled triad genotypes for association studies.Semantic proximity Read ↗

Transmission disequilibrium test with discordant sib pairs when parents are available.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.