Article
A new method to account for missing data in case-parent triad studies.
Human heredity - 1 Jan 2009
Bergemann T L, Huang Z
Abstract excerpt
BACKGROUND/AIMS: The case-parent triad design is commonly used in genetic association studies. Generally, samples are drawn from an affected offspring, manifesting a phenotype of interest, as well as from the parents. The trio genotypes may be analyzed using a variety of available methods, but we focus on log-linear models because they test for genetic association and additionally estimate the relative risks of...
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