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Article

Disentangling pooled triad genotypes for association studies.

Annals of human genetics - 1 Sept 2014

Shi Min, Umbach David M, Weinberg Clarice R

Abstract excerpt

Association studies that genotype affected offspring and their parents (triads) offer robustness to genetic population structure while enabling assessments of maternal effects, parent-of-origin effects, and gene-by-environment interaction. We propose case-parents designs that use pooled DNA specimens to make economical use of limited available specimens. One can markedly reduce the number of genotyping assays...

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Identifiers

PMID: 24962618
DOI: 10.1111/ahg.12073
PMCID: PMC4154801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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