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Article

New approach to association testing in case-parent designs under informative parental missingness.

Genetic epidemiology - 1 Sept 2004

Chen Yi-Hau

Abstract excerpt

The transmission/disequilibrium test (TDT) and related methods using genotype data on diseased probands and their both parents (triads) have been popular for testing linkage or association between a disease and a candidate gene. The usefulness of the TDT-type approaches lies mainly in their robustness, in the sense that they are valid under population stratification, arbitrary parental genotype distribution, and...

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PMID: 15305329
DOI: 10.1002/gepi.20004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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