Article

Dynamic enhancer interactome promotes senescence and aging

2023-05-22

Abstract excerpt

<h4>Summary</h4> Gene expression programs are regulated by enhancers which act in a context-specific manner, and can reside at great distances from their target genes. Extensive three-dimensional (3D) genome reorganization occurs in senescence, but how enhancer interactomes are reconfigured during this process is just beginning to be understood. Here we generated high-resolution contact maps of active enhancers a...

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Literature Corpus work: ffd4b7c4-8301-5756-9c09-dbe67fbd1beb
DOI: 10.1101/2023.05.22.541769

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