Article

MUC4 mutation correlates with tumor mutation burden and the immune microenvironment in colorectal cancer

2020-11-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Immunotherapy is a new strategy for Colorectal cancer (CRC) treatment. Tumor mutation burden (TMB) may act as an emerging biomarker for predicting responses to immunotherapy. Nevertheless, no studies investigate if these gene mutations correlate to TMB and tumor-infiltrating immune cells. <bold>Methods: </bold>Somatic mutation data for CRC samples were obtained...

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Literature Corpus work: ffd0a511-2d99-5d52-a386-d54b72c92e2d
DOI: 10.21203/rs.3.rs-101882/v1

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