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Article

Characterizing and forecasting neoantigens-resulting from MUC mutations in COAD.

Journal of translational medicine - 27 Mar 2024

Chen Min, Zhang Xin, Ming Zihe, Lingyu, Feng Xiaorong, Han Zhenguo, An Han-Xiang

Abstract excerpt

BACKGROUND: The treatment for colon adenocarcinoma (COAD) faces challenges in terms of immunotherapy effectiveness due to multiple factors. Because of the high tumor specificity and immunogenicity, neoantigen has been considered a pivotal target for cancer immunotherapy. Therefore, this study aims to identify and predict the potential tumor antigens of MUC somatic mutations (MUCmut) in COAD. METHODS: Three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38539235
DOI: 10.1186/s12967-024-05103-z
PMCID: PMC10967086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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