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Article

Mutation spectrum in human colorectal cancers and potential functional relevance.

BMC medical genetics - 8 Mar 2013

Yin Hongzhuan, Liang Yichao, Yan Zhaopeng, Liu Baolin, Su Qi

Abstract excerpt

BACKGROUND: Somatic variants, which occur in the genome of all cells, are well accepted to play a critical role in cancer development, as their accumulation in genes could affect cell proliferations and cell cycle. METHODS: In order to understand the role of somatic mutations in human colorectal cancers, we characterized the mutation spectrum in two colorectal tumor tissues and their matched normal tissues, by...

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Identifiers

PMID: 23497483
DOI: 10.1186/1471-2350-14-32
PMCID: PMC3599340

Genes

MUC2
MUC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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