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Exploration of the role of tumor mutation burden in clinical significance, immunotherapy response predictor and immune cell infiltration in colon cancer

2020-06-10

Abstract excerpt

Backgroud:Tumor mutation burden has become a powerful bio-marker to predict prognosis and immunotherapy responsiveness to patients in various cancers, but the role of TMB in colon cancer is still unclear. <h4>Methods:</h4> The transcriptome profiling data of colon patients and the simple nucleotide variation data of colon cases were downloaded from the Cancer Genome Atlas (TCGA) database. The groups were divided i...

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Literature Corpus work
eff96a71-1f7f-53d8-846e-74d0a6fcf9f3
DOI
10.21203/rs.3.rs-31934/v1
Open publication

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Exploration of the role of tumor mutation burden in clinical significance, immunotherapy response predictor and immune cell infiltration in colon cancerDOI 10.21203/rs.3.rs-31934/v1
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