Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploration of the relationship between tumor mutation burden and immune infiltrates in colon adenocarcinoma.

International journal of medical sciences - 1 Jan 2021

Ouyang Rong, Li Zhongzhuan, Peng Peng, Zhang Jinxiu, Liu Jun, Qin Mengbin, Huang Jiean

Abstract excerpt

Background: Tumor mutation burden (TMB) was correlated with the immunotherapeutic response in various malignancies. We aimed to evaluate the TMB immune signature in colon adenocarcinoma (COAD). Methods: Gene expression profile, mutation and clinical data of COAD patients were obtained from The Cancer Genome Atlas (TCGA) database. The samples were divided into high and low TMB level groups to identify...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Antineoplastic Agents, Immunological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Gene Expression Regulation, Neoplastic

Share to Kaplan-Meier Estimate

Share to Lymphocytes, Tumor-Infiltrating

Share to Survival Analysis

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 33437203
DOI: 10.7150/ijms.51918
PMCID: PMC7797534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploration of the relationship between tumor mutation burden and immune infiltrates in colon adenocarcinoma.PMID 33437203Read ↗

Correlations Between Tumor Mutation Burden and Immunocyte Infiltration and Their Prognostic Value in Colon CancerSemantic proximity Read ↗

Integrating tumor mutational burden and transcriptome expression into prediction of immune checkpoint inhibitor response and prognosis of patients with colon cancer.Semantic proximity Read ↗

miRNA-Based Signature Associated With Tumor Mutational Burden in Colon AdenocarcinomaSemantic proximity Read ↗

Exploration of the role of tumor mutation burden in clinical significance, immunotherapy response predictor and immune cell infiltration in colon cancerSemantic proximity Read ↗

Prognostic value of tumor immune cell infiltration patterns in colon adenocarcinoma based on systematic bioinformatics analysisSemantic proximity Read ↗

A MiRNA-based Signature is Associated With Tumor Mutational Burden in Colon AdenocarcinomaSemantic proximity Read ↗

Construction and validation of a colon cancer prognostic model based on tumor mutation burden-related genes.Semantic proximity Read ↗

Identification and Validation of Immune Molecular Subtypes and Immune Landscape Based on Colon Cancer CohortSemantic proximity Read ↗

Analysis of Interleukin-1 Signaling Alterations of Colon Adenocarcinoma Identified Implications for Immunotherapy.Semantic proximity Read ↗

Comprehensive Analysis of Subtype-Specific Molecular Characteristics of Colon Cancer: Specific Genes, Driver Genes, Signaling Pathways, and Immunotherapy ResponsesSemantic proximity Read ↗

Prognostic Biomarker MUC4 Mutations in Colon Adenocarcinoma Correlating with Tumor MicroenvironmentSemantic proximity Read ↗

Two immune-enhanced molecular subtypes differ in inflammation, immune checkpoints, mutations, and prognostic outcome in stage I-II colonic carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.