The type I and III interferon responses restrict infection with tick-borne orthoflaviviruses through IFI6

Abstract excerpt

Tick-borne orthoflaviviruses (TBOVs) are a growing global health concern. Several representatives of this viral family cause fatal disease in humans with increasing case numbers throughout the last decades. The innate immune response, especially interferon (IFN)-dependent signaling, is an essential part of the human defense system that counteracts infection with TBOVs and other viruses. Even though they activate t...

Topics

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• COVID-19 Clinical Research Studies
• Cytokine Signaling Pathways and Interactions
• Hepatitis C virus research
• HIV Research and Treatment
• Influenza Virus Research Studies
• interferon and immune responses
• SARS-CoV-2 and COVID-19 Research
• Viral Infections and Vectors

Identifiers and source

Literature Corpus work

d0642279-5887-599e-952b-34bf672cf51f

DOI

10.1101/2025.04.06.647422