Article

Cell-based screen identifies human type I interferon-stimulated regulators of <i>Toxoplasma gondii</i> Infection

2022-01-02

Abstract excerpt

Macrophages activated with interferons (IFNs) respond with transcriptional changes that enhance clearance of intracellular pathogens such as Toxoplasma , a ubiquitous apicomplexan parasite that infects more than a billion people worldwide. Although IFNs generally inhibit Toxoplasma , the parasite can also induce components of the host IFN signalling pathway to enhance survival in host cells. Compared to the type...

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Literature Corpus work: 5cd8ce23-ddec-56b0-84ea-ab30bffa56af
DOI: 10.1101/2022.01.02.474728

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