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Recent advances in antiviral interferon-stimulated gene biology

12 Mar 2018

Abstract excerpt

The interferon response protects cells from invading viral pathogens by transcriptionally inducing the expression of interferon-stimulated genes (ISGs), some of which encode effectors with varied antiviral functions. As screening technologies improve and mouse model development quickens, more ISGs are continually being identified, characterized mechanistically, and evaluated for protective rolesin vivo. This...

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PMID: 29568506
DOI: 10.12688/f1000research.12450.1

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