Article

Design and specificity of long ssDNA donors for CRISPR-based knock-in

2017-08-21

Abstract excerpt

Update: November 12th, 2019. The conclusions of this pre-print are outdated. See Authors note on page 2. CRISPR/Cas technologies have transformed our ability to manipulate genomes for research and gene-based therapy. In particular, homology-directed repair after genomic cleavage allows for precise modification of genes using exogenous donor sequences as templates. While both single-stranded DNA (ssDNA) and double-...

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Literature Corpus work: ffb6a32d-55d0-5b4f-8d50-ca3e0d4463a4
DOI: 10.1101/178905

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