Article

Chimeric RNA:DNA Donorguide Improves HDR <i>in vitro</i> and <i>in vivo</i>

2021-05-28

Abstract excerpt

Introducing small genetic changes to study specific mutations or reverting clinical mutations to wild type has been an area of interest in precision genomics for several years. In fact, it has been found that nearly 90% of all human pathogenic mutations are caused by small genetic variations, and the methods to efficiently and precisely correct these errors are critically important. One common way to make these sm...

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Literature Corpus work: f0be7c21-d3b7-51f7-ba39-f0f4ee8da8c2
DOI: 10.1101/2021.05.28.446234

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