Article

Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing

2019-08-13

Abstract excerpt

Analysis of circulating cell-free DNA (cfDNA) data has opened new opportunities for characterizing tumour mutational landscapes with many applications in genomic-driven oncology. We developed a customized targeted cfDNA sequencing approach for breast cancer (BC) using unique molecular identifiers (UMIs) for error correction. Our assay, spanning a 284.5 kb target region, is combined with freely-available bioinforma...

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Literature Corpus work: ff6967c6-9686-574d-a89f-d156b6caac52
DOI: 10.1101/733691

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