Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Genomic Profiling of Cell-Free Circulating Tumor DNA Detects Response to Ribociclib Plus Letrozole in a Patient with Metastatic Breast Cancer.

Biomolecules - 6 Dec 2022

Silveira Catarina, Sousa Ana Carla, Corredeira Patrícia, Martins Marta, Sousa Ana Rita, Da Cruz Paula Arnaud, Selenica Pier, Brown David N, Golkaram Mahdi, Kaplan Shannon, Zhang Shile, Liu Li, Weigelt Britta, Reis-Filho Jorge S, Costa Luís, Carmo-Fonseca Maria

Abstract excerpt

Analysis of cell-free circulating tumor DNA obtained by liquid biopsy is a non-invasive approach that may provide clinically actionable information when conventional tissue biopsy is inaccessible or infeasible. Here, we followed a patient with hormone receptor-positive and human epidermal growth factor receptor (HER) 2-negative breast cancer who developed bone metastases seven years after mastectomy. We analyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase Inhibitors
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Circulating Tumor DNA

Share to Genomics

Share to Mastectomy

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 36551247
DOI: 10.3390/biom12121818
PMCID: PMC9775495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Genomic Profiling of Cell-Free Circulating Tumor DNA Detects Response to Ribociclib Plus Letrozole in a Patient with Metastatic Breast Cancer.PMID 36551247Read ↗

The use of cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) to guide treatment selection in metastatic breast cancer.Semantic proximity Read ↗

Next Generation Sequencing of Circulating Cell-Free DNA for Evaluating Mutations and Gene Amplification in Metastatic Breast Cancer.Semantic proximity Read ↗

Targeted deep sequencing revealed variants in cell-free DNA of hormone receptor-positive metastatic breast cancer patientsSemantic proximity Read ↗

Circulating Cell-Free DNA—Diagnostic and Prognostic Applications in Personalized Cancer TherapySemantic proximity Read ↗

Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer PatientsSemantic proximity Read ↗

Testing for oncogenic molecular aberrations in cell-free DNA-based liquid biopsies in the clinic: are we there yet?Semantic proximity Read ↗

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.Semantic proximity Read ↗

Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing.Semantic proximity Read ↗

Detection of genomic alterations in breast cancer with circulating tumour DNA sequencingSemantic proximity Read ↗

Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer Patients.Semantic proximity Read ↗

Targeted Next-Generation Sequencing of Circulating Tumor DNA Mutations among Metastatic Breast Cancer PatientsSemantic proximity Read ↗

Next-generation sequencing in breast cancer: current clinical applications and future directionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.