Article
Circulating Tumor DNA Profiling From Breast Cancer Screening Through to Metastatic Disease.
JCO precision oncology - 1 Jan 2021
Page Karen, Martinson Luke J, Fernandez-Garcia Daniel, Hills Allison, Gleason Kelly L T, Gray Molly C, Rushton Amelia J, Nteliopoulos Georgios, Hastings Robert K, Goddard Kate, Ions Charlotte, Parmar Vilas, Primrose Lindsay, Openshaw Mark R, Guttery David S, Palmieri Carlo, Ali Simak, Stebbing Justin, Coombes R Charles, Shaw Jacqueline A
Abstract excerpt
PURPOSE: We investigated the utility of the Oncomine Breast cfDNA Assay for detecting circulating tumor DNA (ctDNA) in women from a breast screening population, including healthy women with no abnormality detected by mammogram, and women on follow-up through to advanced breast cancer. MATERIALS AND METHODS: Blood samples were taken from 373 women (127 healthy controls recruited through breast screening, 28 ductal...
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