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The potential mechanism and chemical compounds contributed to Psoraleae Fructus-induced hepatotoxicity from the aspect of mitochondrial dysfunction

2023-08-07

Abstract excerpt

<title>Abstract</title> <p>Background Psoraleae Fructus (PF) is a widely-used traditional Chinese medicine in Asia for osteoporosis and vitiligo. The cases of PF-induced hepatotoxicity were frequently reported, which restricted its clinical application. However, the potential hepatotoxic components and the underlying mechanisms remain to be fully elucidated. Methods Kunming mice were intragastrically administra...

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Literature Corpus work
1806550f-81b8-5e01-863f-152f10ec5a82
DOI
10.21203/rs.3.rs-3196333/v1
Open publication

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The potential mechanism and chemical compounds contributed to Psoraleae Fructus-induced hepatotoxicity from the aspect of mitochondrial dysfunctionDOI 10.21203/rs.3.rs-3196333/v1
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