Structural Genomic Rearrangements in Common Cancer Types

Abstract excerpt

The Cancer genome can be used to understand the mechanisms of carcinogenesis and to develop possible therapeutic interventions. Somatic mutations cannot be inherited by next-generation while mutations in germ line cells will be transmitted to the next progeny. One of the important cancer genome databases is Cancer Genome Atlas (TCGA) created by using modern sequencing technology to identify the somatic variations...

Topics

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• Cancer Genomics and Diagnostics
• Genome, Human
• Genomic Structural Variation
• Genomics
• High-Throughput Nucleotide Sequencing
• Mutation
• Neoplasms
• Prevalence

Identifiers and source

Literature Corpus work

feaea65c-b2ad-5e59-9f24-78c4e7e252a9

DOI

10.21203/rs.3.rs-2498681/v1