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Article

Diverse mechanisms of somatic structural variations in human cancer genomes.

Cell - 9 May 2013

Yang Lixing, Luquette Lovelace J, Gehlenborg Nils, Xi Ruibin, Haseley Psalm S, Hsieh Chih-Heng, Zhang Chengsheng, Ren Xiaojia, Protopopov Alexei, Chin Lynda, Kucherlapati Raju, Lee Charles, Park Peter J

Abstract excerpt

Identification of somatic rearrangements in cancer genomes has accelerated through analysis of high-throughput sequencing data. However, characterization of complex structural alterations and their underlying mechanisms remains inadequate. Here, applying an algorithm to predict structural variations from short reads, we report a comprehensive catalog of somatic structural variations and the mechanisms generating...

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Identifiers

PMID: 23663786
DOI: 10.1016/j.cell.2013.04.010
PMCID: PMC3704973

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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