Article
Patterns of structural variation in human cancer
2017-08-27
Abstract excerpt
<h4>ABSTRACT</h4> A key mutational process in cancer is structural variation, in which rearrangements delete, amplify or reorder genomic segments ranging in size from kilobases to whole chromosomes. We developed methods to group, classify and describe structural variants, applied to >2,500 cancer genomes. Nine signatures of structural variation emerged. Deletions have trimodal size distribution; assort unevenly a...
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Identifiers and source
- Literature Corpus work
- 6b18dc5b-03ac-54fd-ba46-b70184203a6c
- DOI
- 10.1101/181339