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Article

An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral Load

19 Jun 2014

Abstract excerpt

Trends in HIV virulence have been monitored since the start of the AIDS pandemic, as studying HIV virulence informs our understanding of HIV epidemiology and pathogenesis. Here, we model changes in HIV virulence as a strictly evolutionary process, using set point viral load (SPVL) as a proxy, to make inferences about empirical SPVL trends from longitudinal HIV cohorts. We develop an agent-based epidemic model...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24945322
DOI: 10.1371/journal.pcbi.1003673

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