Article

Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming

2017-10-17

Abstract excerpt

The fate and function of epigenetic marks during the germline-to-embryo transition is a key issue in developmental biology, with relevance to stem cell programming and trans-generational inheritance. In zebrafish, DNA methylation (DNAme) patterns are programmed in transcriptionally-quiescent cleavage embryos; remarkably, paternally-inherited patterns are maintained, whereas maternal patterns are reprogrammed to ma...

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Literature Corpus work: fe4828ab-f1d4-5e2f-a986-642700d42fbe
DOI: 10.1101/204792

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